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Gert studied biochemistry at the university of Utrecht, and got his PhD in 1983 at the agricultural university of Wageningen. He post-doc-ed in Purdue, Indiana, USA, and in Groningen, The Netherlands where he started the WHAT IF project. From 1989-1999 he worked at the EMBL where he continued working on (and with) WHAT IF.
In the summer of 1999 he took up a position at the Radboud University Nijmegen, The Netherlands where he built-up the CMBI. At the CMBI Gert continued working on fundamental and applied aspects of protein structure (homology modelling, structure quality, visualization, molecular dynamics, ligand interactions) and of information technology (data-mining, information systems). The 2007 move of the CMBI from the science faculty to the Medical Centre of the Radboud University allowed for more emphasis on the application of bioinformatics in biomedical research.